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What is a 17-HYDROXYPROGESTERONE (17-OHP)?

17-Hydroxyprogesterone (17-OHP) is a blood test that measures the level of a steroid hormone produced mainly by the adrenal glands and involved in cortisol production. The test is primarily needed to screen for or evaluate congenital adrenal hyperplasia (CAH), particularly 21-hydroxylase deficiency. It may also help investigate symptoms such as excessive androgen production, irregular menstruation, early puberty, or unexplained hormonal abnormalities.

Additional Information

Also known as/ Other names: 17-OHP test, 17-OH progesterone test, 17α-hydroxyprogesterone test, Progesterone – 17-OH, 17 hydroxy progesterone: serum
Parameters: 1
Recommended for: M/F/Others
Sample Type: Blood
Patient Preparation: No prior preparation is needed
Reports: Next Day

FAQs

What is congenital adrenal hyperplasia (CAH)?

CAH is a group of inherited conditions affecting adrenal steroid hormone production. The most common form is caused by reduced activity of the 21-hydroxylase enzyme.

What does a high 17-OHP level mean?

Elevated 17-OHP may occur with congenital adrenal hyperplasia or increased adrenal steroid production. Interpretation depends on age, gender, symptoms, timing, and the laboratory reference range.

What does a low 17-OHP level mean?

A low result is generally less concerning for CAH, but interpretation depends on the reason for testing and other hormone results.

Can adults have a 17-OHP test?

Yes. Adults may be tested when CAH is suspected or when symptoms such as excess androgen production, irregular menstrual cycles, or unexplained hormonal abnormalities require evaluation.

Can children have a 17-OHP test?

Yes. It may be performed in newborns, children, or adolescents when screening for CAH or evaluating signs of abnormal adrenal or sexual development.

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