Absolute Lymphocyte Count (ALC) is a blood test that measures the actual number of lymphocytes, a type of white blood cell essential for immune defense. The test is needed to assess immune system function and investigate abnormal lymphocyte levels, which may occur with infections, immune disorders, certain medications, or blood-related conditions. ALC can also help monitor changes in immune status and response to treatment when clinically indicated.
Lymphocytes are immune cells that include B cells, T cells, and natural killer (NK) cells. They help the body recognize and respond to infections and other abnormal cells.
An elevated ALC, called lymphocytosis, can occur with viral infections, some bacterial infections, immune conditions, and certain blood or lymphatic disorders.
A low ALC, called lymphocytopenia or lymphopenia, may occur with certain infections, immune disorders, nutritional problems, medications, or conditions affecting the bone marrow or immune system.
Significant physical stress, acute illness, or physiological stress responses can temporarily alter white blood cell and lymphocyte levels.
Yes. Many infections can temporarily change lymphocyte levels. Viral infections commonly increase lymphocytes, although some infections can cause a decrease.