Absolute Neutrophil Count (ANC) is a blood test that measures the number of neutrophils, white blood cells that provide a first line of defense against bacterial and fungal infections. The test is needed to assess immune defense, investigate abnormal white blood cell counts, and determine infection risk, particularly in people receiving chemotherapy or certain medications. ANC is also useful for monitoring bone marrow function and treatment-related changes.
Neutrophils are a type of white blood cell that provides an important first-line defense against many bacterial and fungal infections.
A low ANC is called neutropenia. It can increase susceptibility to infections, particularly when the neutrophil count becomes significantly reduced.
An elevated ANC may occur in response to infections, inflammation, physical stress, certain medications, or other conditions that stimulate neutrophil production.
Neutropenia refers to an abnormally low number of neutrophils in the blood. Its severity and clinical significance depend on the ANC level and the underlying cause.
Causes may include viral infections, certain medications, chemotherapy, nutritional deficiencies, autoimmune conditions, and disorders affecting bone marrow production.
High neutrophil counts can occur with bacterial infections, inflammation, physical stress, smoking, corticosteroid use, and some other medical conditions.