Please be aware that Mahajan Imaging & Labs will never request for your bank details or OTP for booking/registration purposes.

What is a ADAMTS13 ACTIVITY by CLIA?

The ADAMTS13 Activity by CLIA test is a specialized blood test that measures the activity of the ADAMTS13 enzyme using Chemiluminescent Immunoassay (CLIA) technology. ADAMTS13 plays a crucial role in regulating blood clotting by breaking down von Willebrand factor. Low activity levels are strongly associated with thrombotic thrombocytopenic purpura (TTP), a rare but life-threatening condition. This test is performed to confirm suspected TTP, guide treatment decisions, and monitor disease progression or response to therapy.

Additional Information

Also known as/ Other names: ADAMTS13 Activity Assay (CLIA method), ADAMTS13 Functional Activity Test, ADAMTS13 Enzyme Activity Analysis, ADAMTS13 Activity (Chemiluminescent Immunoassay), von Willebrand Factor–Cleaving Protease Activity Test
Parameters: 1
Recommended for: M/F/Others
Sample Type: Whole blood in 2 Blue Top (Sodium Citrate) tube
Patient Preparation: Overnight fasting is preferred
Reports: 5 Days

FAQs

Why is this test important?

It identifies reduced ADAMTS13 activity, which is strongly linked to TTP. Early detection allows timely treatment, preventing life-threatening complications like organ damage and severe clotting.

Who should undergo this test?

Patients with unexplained anemia, low platelets, neurological symptoms, or suspected TTP are recommended to undergo this test for accurate diagnosis and management.

What happens if the test is positive?

Low ADAMTS13 activity suggests TTP. Doctors may recommend plasma exchange or immunosuppressive therapy to restore enzyme function and prevent complications.

What does a negative result mean?

Normal ADAMTS13 activity reduces the likelihood of TTP, but other clotting disorders may still need investigation.

Can medications affect the test results?

Yes, certain treatments like plasma exchange or immunosuppressive drugs may influence enzyme activity. Inform your doctor about all medications before testing.

What are the risks of not testing?

Without testing, undiagnosed TTP can lead to severe clotting, organ failure, and potentially fatal outcomes.

Can TTP be prevented?

TTP cannot always be prevented, but early detection through this test allows timely treatment to reduce risks and complications.

Recommend more for you

Book Your Test
Text copied to clipboard
Dynamic badges will be added here