ADH (Antidiuretic Hormone), also known as vasopressin, is a blood test that measures the level of this hormone, which helps regulate the body’s water balance and blood pressure. The test is needed to evaluate disorders of water regulation, particularly when diabetes insipidus or inappropriate ADH secretion (SIADH) is suspected. The sample required for this test is EDTA plasma, collected through a routine blood draw.
ADH is a hormone produced in the hypothalamus and released from the posterior pituitary gland. It helps the kidneys conserve water and maintain fluid balance.
Vasopressin is another name for antidiuretic hormone (ADH). It plays an important role in regulating water retention and, at higher concentrations, blood vessel constriction.
A high ADH level may occur when the body is retaining too much water or when ADH secretion is inappropriate, as can occur in SIADH. Interpretation depends on blood sodium, osmolality, and hydration status.
A low ADH level may be associated with certain forms of central diabetes insipidus, in which the body cannot produce or release sufficient ADH.
Diabetes insipidus is a condition involving impaired ADH activity, leading to excessive urination and thirst. It can result from insufficient ADH production or reduced kidney response to the hormone.
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