Anti-DNase B is a blood test that measures antibodies produced by the immune system against DNase B, an enzyme made by Streptococcus bacteria. It helps provide evidence of a recent or previous streptococcal infection, particularly when the initial infection has resolved. The test is needed when evaluating possible post-streptococcal complications such as rheumatic fever or post-streptococcal glomerulonephritis.
No. The test measures antibodies rather than the bacteria themselves. Tests such as throat culture or rapid antigen testing may be more appropriate for suspected active throat infection.
Anti-DNase B levels can increase following infections caused by group A Streptococcus, including throat and some skin infections.
Yes. It can provide evidence of a preceding streptococcal infection when evaluating conditions such as post-streptococcal glomerulonephritis.
Antibody levels generally increase after the initial infection rather than immediately. The timing varies, so results should be interpreted according to the patient's symptoms and clinical history.
It means the antibody level is within the laboratory's reference range. However, a normal result does not always completely exclude a previous streptococcal infection.
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