What is a ANTI-IgLON5 ANTIBODY IgG?

The Anti-IgLON5 Antibody IgG test is a specialized blood test used to detect antibodies against the neuronal cell adhesion protein IgLON5. The presence of these antibodies is associated with a rare neurological disorder known as anti-IgLON5 disease, which can cause sleep disturbances, movement abnormalities, and progressive neurodegeneration. Doctors order this test to confirm suspected cases, differentiate it from other autoimmune or neurodegenerative conditions, and guide appropriate treatment strategies for patients presenting with unexplained neurological symptoms.