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What is a ANTI THROMBIN ACTIVITY, FUNCTIONAL?

Anti-Thrombin Activity, Functional is a blood test that measures the ability of antithrombin, a natural anticoagulant protein, to inhibit clotting factors and help prevent excessive blood clot formation. The test is needed to evaluate suspected antithrombin deficiency, particularly in individuals with unexplained or recurrent blood clots at a young age. It may also help investigate unusual thrombotic events or assess abnormal coagulation findings.

Additional Information

Also known as/ Other names: Antithrombin Activity Test, AT Activity – Functional Assay, Antithrombin III Activity, Functional Antithrombin Assay, ATIII Activity – Plasma, Antithrombin Functional Test
Parameters: 1
Recommended for: M/F/Others
Sample Type: Blood
Patient Preparation: Overnight fasting is preferred
Reports: 2 Days

FAQs

What is antithrombin?

Antithrombin is a protein produced mainly by the liver that naturally limits blood clotting by inhibiting important clotting factors, particularly thrombin and factor Xa.

What does a low antithrombin activity result mean?

Low activity may indicate reduced antithrombin function and can increase the risk of abnormal blood clot formation. Further testing may be required to determine the cause.

What does a normal antithrombin activity result mean?

A normal result indicates that antithrombin is functioning within the laboratory's reference range at the time of testing.

Does low antithrombin activity mean I will develop a blood clot?

Not necessarily. Deficiency can increase the risk of thrombosis, but whether a clot develops depends on several genetic and acquired risk factors.

Is antithrombin deficiency inherited?

Yes. Antithrombin deficiency can be inherited due to changes in the SERPINC1 gene. However, reduced antithrombin levels can also occur because of acquired medical conditions.

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