C-Peptide Post Prandial Serum is a blood test that measures C-peptide levels after eating, providing an estimate of the insulin produced naturally by the pancreas. Since C-peptide is released alongside insulin, it helps assess pancreatic beta-cell function and endogenous insulin production. The test is useful in evaluating diabetes, distinguishing between different types of diabetes, assessing residual insulin production, and investigating unexplained low blood sugar.
Injected insulin does not contain C-peptide, so it generally does not directly increase measured C-peptide. However, insulin treatment can influence the body's own insulin production and therefore affect interpretation.
Insulin measures insulin present in the blood, while C-peptide reflects naturally produced insulin because it is released alongside endogenous insulin. C-peptide can therefore be useful when assessing pancreatic insulin production.
Yes. C-peptide can help determine whether the body is producing its own insulin during an episode of low blood sugar, particularly when inappropriate insulin production is suspected.
A high level may indicate that the pancreas is producing substantial insulin. It can occur with insulin resistance, certain metabolic conditions, or other situations involving increased insulin production.
A low level may indicate reduced insulin production by the pancreas. It can be seen when pancreatic beta-cell function is significantly impaired, such as in some people with type 1 diabetes.
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