CD14 Flow Cytometry is a laboratory test that detects and measures CD14, a cell-surface marker primarily expressed on monocytes and macrophages. Using flow cytometry, it helps identify and characterize monocyte populations and other cells in blood, bone marrow, or tissue samples. The test is needed to support the evaluation and classification of certain leukemias, myeloid disorders, and other hematological conditions by identifying abnormal cellular patterns.
CD14 may be included when evaluating suspected acute myeloid leukemia, chronic myelomonocytic leukemia, monocytic disorders, or other conditions involving abnormal myeloid cell populations.
No. CD14 is one marker used as part of a broader immunophenotyping panel. Diagnosis requires correlation with other markers, blood counts, cell morphology, clinical findings, and sometimes genetic testing.
Cells from the specimen are treated with antibodies that bind to CD14 and other relevant markers. A flow cytometer analyzes the cells and identifies their marker-expression patterns.
CD14-positive means that the tested cells express the CD14 marker. The significance depends on the type and proportion of cells showing expression and the results of other markers.
CD14-negative means that significant CD14 expression was not detected in the evaluated population. The result should be interpreted in conjunction with the complete flow-cytometry profile.
OTP sent to your mobile number on whatsapp
Didn't recieved OTP Yet? Resend OTP
