CD15 Flow Cytometry is a laboratory test that detects and measures CD15, a cell-surface marker expressed on various myeloid cells and some abnormal lymphoid cells. Using flow cytometry, it helps identify and characterize specific cell populations in blood, bone marrow, or tissue samples. The test is needed to support the diagnosis and classification of certain leukemias, lymphomas, and other hematological disorders by evaluating cellular marker patterns.
No. CD15 is one marker used in a broader immunophenotyping panel. Diagnosis requires correlation with other markers, blood counts, morphology, clinical findings, and sometimes genetic or molecular tests.
CD15 may be included when evaluating suspected acute myeloid leukemia, myeloid neoplasms, certain lymphomas, or other disorders involving abnormal hematopoietic cell populations.
CD15-positive means that the evaluated cells express the CD15 marker. The significance depends on the cell type, intensity of expression, and results of other immunophenotyping markers.
CD15-negative means significant CD15 expression was not detected in the tested cell population. This finding must be interpreted alongside other markers and clinical information.
Yes. CD15 is normally expressed on several myeloid cells, particularly granulocytes and some monocytes. Abnormal expression patterns can provide additional information during flow-cytometry evaluation.
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