CD19 Flow Cytometry is a laboratory test that detects and measures CD19, a protein expressed primarily on B lymphocytes. Using flow cytometry, it helps identify and characterize B-cell populations in blood, bone marrow, or other specimens. The test is needed to determine B-cell lineage and support the diagnosis and classification of B-cell leukemias, lymphomas, and other lymphoproliferative disorders by identifying abnormal cellular patterns.
It can assist in evaluating B-cell leukemias, non-Hodgkin lymphomas, chronic lymphocytic leukemia, and other conditions involving abnormal or increased B-cell populations.
No. CD19 is one marker within an immunophenotyping panel. A diagnosis requires correlation with other markers, clinical findings, blood or bone marrow results, and sometimes tissue examination.
CD19-positive means that the evaluated cells express CD19. The finding helps establish B-cell lineage, but its clinical significance depends on the overall cell population and other marker results.
CD19-negative means that significant CD19 expression was not detected in the evaluated cell population. This may have different implications depending on the cell type and suspected condition.
Yes. CD19 is expressed on most B-cell populations from early B-cell development through mature B cells, although expression can vary during different stages of B-cell development.
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