CD20 Flow Cytometry is a laboratory test that detects and measures the expression of CD20, a protein commonly found on B lymphocytes. Using flow cytometry, it helps identify and characterize B-cell populations in blood, bone marrow, or other specimens. The test is needed to support the diagnosis and classification of B-cell leukemias, lymphomas, and other lymphoproliferative disorders by identifying abnormal patterns of cellular markers.
The test helps identify abnormal B-cell populations and supports the diagnosis and classification of B-cell leukemias, lymphomas, and other lymphoproliferative disorders.
CD20 testing can contribute to the evaluation of several B-cell disorders, including chronic lymphocytic leukemia, non-Hodgkin lymphomas, and other B-cell lymphoproliferative conditions.
No. CD20 is only one component of an immunophenotyping panel. Diagnosis requires correlation with other markers, clinical findings, blood or bone marrow results, and sometimes tissue biopsy.
CD20-positive means that the tested cells express CD20 on their surface. The significance depends on the type and proportion of cells showing expression and other marker results.
CD20-negative means that significant CD20 expression was not detected in the evaluated population. This finding must be interpreted alongside the complete immunophenotyping profile.
Yes. CD20 is commonly expressed on many mature B lymphocytes. Its expression pattern can help laboratories identify B-cell populations and distinguish them from other lymphocyte types.
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