CD23 Flow Cytometry is a laboratory test that uses flow cytometry to detect and measure CD23, a protein expressed on the surface of certain B lymphocytes. It helps identify and characterize abnormal lymphocyte populations in blood, bone marrow, or other samples. The test is commonly used as part of immunophenotyping to support the diagnosis and classification of lymphoproliferative disorders, including certain types of leukemia and lymphoma.
CD23 expression can be useful when evaluating disorders involving B lymphocytes, including chronic lymphocytic leukemia and some types of B-cell lymphoma.
No. CD23 is one marker among several used in immunophenotyping. Diagnosis requires correlation with other flow-cytometry markers, blood or bone marrow findings, clinical history, and sometimes biopsy results.
CD23 positivity means that a population of cells expresses the CD23 marker. Its significance depends on the type of cells involved and the pattern of other markers detected.
CD23 negativity indicates that the tested cell population does not show significant CD23 expression. This finding must be interpreted alongside the complete immunophenotyping profile.
Yes. CD23 is commonly expressed in chronic lymphocytic leukemia cells and can be an important marker when distinguishing CLL from other B-cell lymphoproliferative disorders.
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