Cytomegalovirus (CMV) Antibodies Panel IgG & IgM is a blood test that detects IgG and IgM antibodies produced in response to CMV infection. Testing both antibodies helps assess whether a person has been exposed to CMV and may provide clues about the timing of infection. It is needed to evaluate suspected CMV infection, particularly during pregnancy, in newborns, or in individuals with weakened immunity.
CMV is a common virus from the herpesvirus family. After infection, it can remain in the body in an inactive state and may reactivate later.
A positive IgG result generally indicates previous exposure to CMV. IgG can remain detectable for life after infection.
A positive IgM result may occur with a recent primary infection, reactivation, or reinfection. It does not by itself confirm when the infection occurred.
This pattern can occur during a recent infection, reactivation, or persistent IgM response. Additional testing may be needed to determine the timing and significance.
This generally indicates previous CMV exposure without evidence of a current IgM response. Clinical context may still be important.
This may indicate a very recent infection, but false-positive IgM results can occur. Repeat or additional testing may be recommended.
It generally suggests no detectable previous CMV exposure or recent antibody response at the time of testing. Very early infection may not yet produce detectable antibodies.