Dexamethasone Suppression test Low dose For Cortisol

Dexamethasone is a synthetic corticosteroid that acts similarly to cortisol. In healthy individuals, a low dose normally reduces the body's cortisol production.

Cortisol is a hormone produced by the adrenal glands that helps regulate metabolism, blood pressure, blood sugar, immune responses, and the body's response to stress.

Appropriate suppression generally suggests that cortisol production is responding normally to dexamethasone, making autonomous cortisol excess less likely.

Failure to suppress may indicate excessive or autonomous cortisol production and can support further evaluation for Cushing syndrome.