DHEA-S is a blood test that measures the level of dehydroepiandrosterone sulphate, a hormone produced primarily by the adrenal glands and involved in the production of sex hormones. The test is needed to assess adrenal androgen production and investigate symptoms such as excessive hair growth, acne, irregular menstrual cycles, early puberty, or signs of hormonal imbalance. It can also help evaluate certain adrenal gland disorders and tumors.
DHEA-S is the sulfated form of DHEA. It is produced primarily by the adrenal glands and serves as a precursor for the production of other steroid hormones.
Elevated DHEA-S may indicate increased adrenal androgen production. Possible causes include congenital adrenal hyperplasia, certain adrenal disorders, or, less commonly, an adrenal androgen-producing tumor.
Low levels may occur with reduced adrenal function, certain pituitary disorders, or naturally with aging. The result should be interpreted according to age, gender, symptoms, and other hormone tests.
Symptoms may include excessive facial or body hair, acne, irregular or absent menstrual periods, scalp hair loss, or other signs of increased androgen activity.