Estradiol (E2) Serum is a blood test that measures the level of estradiol, the primary form of estrogen in females and an important reproductive hormone in all sexes. Estradiol plays a role in menstrual cycles, ovulation, fertility, bone health, and sexual development. The test is needed to evaluate hormonal imbalances, menstrual irregularities, fertility concerns, ovarian function, and certain reproductive or endocrine disorders.
Estradiol, also called E2, is a major estrogen hormone. It plays important roles in reproductive development, ovulation, menstrual cycles, bone health, and other biological functions.
Yes. Estradiol is present in males as well. It is produced in smaller amounts and contributes to bone health, reproductive function, and other physiological processes.
Estradiol helps regulate the menstrual cycle and ovulation and supports reproductive health. Levels naturally change throughout the menstrual cycle and decline significantly after menopause.
Elevated estradiol can have different causes depending on age, sex, menstrual-cycle phase, pregnancy status, medications, and health conditions. Results should be interpreted within the appropriate clinical context.
Low levels may occur naturally after menopause or with reduced ovarian function. They can also be associated with certain hormonal, nutritional, or endocrine conditions.