G-6-PD Quantitative is a blood test that measures the activity level of glucose-6-phosphate dehydrogenase (G6PD), an enzyme that protects red blood cells from oxidative damage. The test is primarily used to identify G6PD deficiency, an inherited condition that can cause red blood cell breakdown (hemolysis). It is needed to assess unexplained anemia or jaundice and help guide safe use of certain medicines and treatments.
Yes. G6PD deficiency is usually inherited through the X chromosome, so it is more commonly expressed in males, although females can also be affected.
G6PD helps red blood cells protect themselves from oxidative stress. Adequate enzyme activity helps maintain red blood cell integrity and prevents premature destruction.
A low G6PD activity level may indicate G6PD deficiency. The result should be interpreted alongside symptoms, medical history, and the laboratory's reference range.
Certainly. When red blood cells are exposed to oxidative stress, they may break down faster than the body can replace them, potentially causing hemolytic anemia.
Yes. Rapid breakdown of red blood cells can increase bilirubin levels, which may result in yellowing of the skin or eyes.