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What is a GLUCAGON STIMULATION TEST FOR C PEPTIDE?

The Glucagon Stimulation Test for C-Peptide is a dynamic blood test that evaluates the pancreas’s ability to produce insulin by measuring C-peptide levels before and after glucagon administration. It helps assess residual beta-cell function and insulin production, particularly in people with diabetes. The test may be needed to distinguish between different types of diabetes, evaluate pancreatic insulin reserve, and support decisions regarding treatment and disease management.

Additional Information

Also known as/ Other names: C-Peptide Stimulation Test, Glucagon C-Peptide Test, Stimulated C-Peptide Test, Glucagon Provocation Test for C-Peptide
Parameters: 1
Recommended for: M/F/Others
Sample Type: Blood
Patient Preparation: Basal fasting C peptide levels, 5 min, 10 min, 15 min C peptide levels after 1 mg of IV glucagon injection.
Reports: Next Day

FAQs

What is C-peptide?

C-peptide is released by the pancreas in equal amounts with endogenous insulin. Measuring it provides an indication of how much insulin the body is producing naturally.

What is glucagon?

Glucagon is a hormone that normally raises blood glucose levels by stimulating the liver to release stored glucose. During this test, it is used to stimulate insulin secretion.

What does the test tell about pancreatic function?

It helps determine how effectively pancreatic beta cells can respond to stimulation and produce insulin, providing information about the body's remaining insulin-producing capacity.

Who may be advised to undergo this test?

It may be recommended for people with diabetes when the amount of natural insulin production is uncertain or when distinguishing between different forms of diabetes is clinically important.

What is the purpose of measuring C-peptide after glucagon?

Stimulated C-peptide reflects the pancreas's response to a controlled stimulus and can provide a clearer assessment of insulin-producing beta-cell reserve than a single baseline measurement.

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