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What is a HAINS MYCOBACTERIUM TUBERCULOSIS FIRST AND SECOND LINE DRUG RESISTANCE PROFILE?

The **HAINS Mycobacterium Tuberculosis First and Second Line Drug Resistance Profile** is an advanced molecular diagnostic test that detects genetic mutations in *Mycobacterium tuberculosis* associated with resistance to both first-line drugs (like rifampicin and isoniazid) and second-line drugs (such as fluoroquinolones and aminoglycosides). Using line probe assay technology, it provides rapid and accurate identification of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB strains. This test is performed to guide clinicians in tailoring effective treatment regimens, improving patient outcomes, and preventing the spread of resistant tuberculosis.

Additional Information

Also known as/ Other names: TB First & Second Line Drug Resistance Test, Mycobacterium Tuberculosis Drug Resistance Line Probe Assay, MDR/XDR TB Resistance Molecular Panel
Parameters: 1
Recommended for: M/F/Others
Sample Type: Positive Culture Growth
Patient Preparation: No prior preparation is needed
Reports: Next Saturday

FAQs

What does a positive resistance result mean?

It indicates TB bacteria carry mutations making them resistant to specific drugs, requiring alternative treatment strategies.

What does a negative resistance result mean?

It suggests no detectable resistance mutations, meaning standard TB drugs may be effective.

Who should undergo this test?

Patients with suspected TB, especially those not responding to treatment or at risk of drug resistance, should undergo this test.

Can this test detect MDR-TB?

Yes, it identifies resistance to rifampicin and isoniazid, the two key drugs defining multidrug-resistant TB.

Can this test detect XDR-TB?

Yes, it also detects resistance to second-line drugs like fluoroquinolones and aminoglycosides, confirming extensively drug-resistant TB.

Does resistance always mean treatment failure?

Yes, resistance to key drugs requires alternative regimens, as standard therapy may not work.

Can this test prevent TB spread?

Certainly, rapid detection of resistant strains helps doctors adjust treatment quickly, reducing transmission risk.

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