Hereditary Nonpolyposis Colorectal Cancer / Lynch Syndrome
MRP - ₹ 27,450
What is a Hereditary Nonpolyposis Colorectal Cancer / Lynch Syndrome?
Hereditary Nonpolyposis Colorectal Cancer (HNPCC) / Lynch Syndrome Panel is a genetic test that analyzes key mismatch repair (MMR) genes such as MLH1, MSH2, MSH6, PMS2, and EPCAM for germline mutations.
This panel is used to diagnose Lynch syndrome, an inherited condition that significantly increases the lifetime risk of colorectal cancer, endometrial cancer, and several other cancers. It helps in early identification of at-risk individuals, enabling personalized surveillance, preventive strategies, and family screening for better cancer prevention and management.
Additional Information
| Also known as/ Other names: | Lynch Syndrome Genetic Test, HNPCC Genetic Panel, Hereditary Colorectal Cancer Panel, Mismatch Repair (MMR) Gene Panel |
| Parameters: | 1 |
| Recommended for: | M/F/Others |
| Sample Type: | Blood |
| Patient Preparation: | Minimum gap from Chemotherapy should be 2 weeks |
| Reports: | 4-6 weeks |
FAQs
While not completely preventable, regular screenings and early detection significantly reduce cancer complications and improve treatment outcomes in high-risk individuals.
Genetic counseling helps patients understand the benefits, limitations, possible outcomes, and implications of the test for themselves and their families.
Certainly, close relatives may carry the same mutation and can benefit from early screening, preventive care, and genetic counseling.
Lynch Syndrome testing is highly accurate for detecting known gene mutations, though rare variants or undiscovered mutations may occasionally remain unidentified.
Lynch Syndrome is inherited and linked to gene mutations, while sporadic colorectal cancer develops without a known hereditary genetic cause.
Certainly, each child of a parent carrying a Lynch Syndrome mutation has a 50% chance of inheriting the condition.
