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What is a HOMA-IR (HOMEOSTATIC MODEL ASSESSMENT OF INSULIN RESISTANCE)?

HOMA-IR is a calculated measure used to estimate insulin resistance by assessing fasting insulin and fasting blood glucose levels. It provides an indication of how effectively the body responds to insulin and helps evaluate metabolic health. The test is needed to identify or monitor insulin resistance, which may be associated with prediabetes, type 2 diabetes, obesity, polycystic ovary syndrome (PCOS), and other metabolic disorders.

Additional Information

Also known as/ Other names: Insulin Resistance Test (HOMA-IR), Homeostatic Model Assessment Test, HOMA Index, Insulin Sensitivity Test, Glucose-Insulin Ratio Test
Parameters: 3
Recommended for: M/F/Others
Sample Type: Blood
Patient Preparation: Overnight fasting is mandatory
Reports: Same day

FAQs

How is HOMA-IR calculated?

HOMA-IR is calculated using fasting glucose and fasting insulin values. The exact formula and units used can vary depending on the laboratory and measurement system.

What does a high HOMA-IR value mean?

A higher HOMA-IR value may suggest reduced insulin sensitivity or insulin resistance. Interpretation should use the laboratory's reference range and consider the individual's clinical circumstances.

What does a low HOMA-IR value mean?

A lower value generally indicates better insulin sensitivity, although the result should be interpreted alongside fasting glucose, insulin, symptoms, and other metabolic findings.

Can HOMA-IR diagnose diabetes?

No. HOMA-IR is not a standalone diagnostic test for diabetes. Tests such as fasting plasma glucose, HbA1c, or an oral glucose tolerance test are commonly used for diagnosis.

Can HOMA-IR identify prediabetes?

HOMA-IR may provide information about insulin resistance, but it does not independently diagnose prediabetes. Standard glucose-based tests are generally used to establish a prediabetes diagnosis.

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