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What is a MANTOUX?

The Mantoux test, also known as the tuberculin skin test, is a diagnostic tool used to detect latent or active tuberculosis infection. It involves injecting a small amount of purified protein derivative (PPD) under the skin of the forearm and observing the reaction after 48–72 hours. The test helps identify whether a person has been exposed to *Mycobacterium tuberculosis*, making it an important screening method for TB control and prevention programs worldwide.

Additional Information

Also known as/ Other names: Mantoux Test, Tuberculin Skin Test (TST), PPD Skin Test, Tuberculosis Skin Test
Parameters: 1
Recommended for: M/F/Others
Sample Type: NA
Patient Preparation: Patient should report to the lab on day 1 for intra dermal injection followed by reading 48 to 72 hrs post injection. Patient should avoid itching on Injected site, washing with soap till reading is taken.
Reports: 48-72 hrs post injection

FAQs

How is the Mantoux test performed?

A small amount of PPD is injected intradermally into the forearm. The injection site is then examined after 48–72 hours for swelling or induration.

What does a positive Mantoux test mean?

A positive result indicates prior exposure to Mycobacterium tuberculosis. It does not confirm active disease but suggests latent infection or past contact with tuberculosis bacteria.

Who should undergo the Mantoux test?

It is recommended for individuals at risk of tuberculosis, including healthcare workers, close contacts of TB patients, or those with weakened immune systems due to medical conditions.

Are there limitations of the Mantoux test?

Yes, false positives may occur in people vaccinated with BCG, and false negatives can appear in immunocompromised individuals, so results must be interpreted with clinical context.

Can the Mantoux test diagnose active tuberculosis?

No, it only indicates exposure or latent infection. Active tuberculosis requires further investigations like chest X‑ray, sputum tests, or molecular diagnostics for confirmation.

What factors can affect Mantoux test accuracy?

BCG vaccination, immunosuppression, malnutrition, or recent TB infection can influence results, leading to false positives or false negatives that require careful interpretation.

What happens if the test is negative?

A negative result usually means no TB exposure. However, in immunocompromised individuals, false negatives are possible, so further evaluation may still be necessary.

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