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What is a MATERNAL SERUM SCREEN 4; QUADRUPLE TEST?

Maternal Serum Screen 4, also called the Quadruple Test, is a blood test done during pregnancy to check levels of four substances in the mother’s blood. It is needed to assess the baby’s risk of certain chromosomal conditions such as Down syndrome and Trisomy 18, as well as neural tube defects like spina bifida, so that further evaluation can be planned if required.

Additional Information

Also known as/ Other names: Quadruple Marker Test, Quad Screen Test, Maternal Quadruple Screening, Prenatal Quad Marker Test
Parameters: 1
Recommended for: Female
Sample Type: Blood
Patient Preparation: Acceptable between 14 to 22 weeks + 6 days gestation. USG is mandatory must include BPD & referring doctor.
Reports: Same Day

FAQs

When is the quadruple test usually done?

It is generally performed in the second trimester, usually between 15 and 22 weeks of pregnancy.

Is the quadruple test a diagnostic test?

No, it only estimates risk. It cannot confirm whether the baby has a genetic condition.

What substances are measured in this test?

The test measures AFP, hCG, unconjugated estriol, and inhibin A.

What conditions can this test help detect?

It helps assess the risk of Down syndrome, Trisomy 18, and open neural tube defects.

What does a high-risk result mean?

A high-risk result means the chance of a chromosomal or birth defect may be higher, and further testing may be advised.

What does a low-risk result mean?

A low-risk result means the chance of the condition is lower, but it does not guarantee a completely normal pregnancy.

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