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What is a METANEPHRINES 24 HRS URINE?

The **Metanephrines 24‑hour Urine test** is a specialized diagnostic test that measures the levels of metanephrines, which are breakdown products of adrenaline and noradrenaline, in urine collected over 24 hours. Elevated levels may indicate pheochromocytoma or paraganglioma, rare tumors that produce excess catecholamines. This test is performed to help diagnose these conditions, monitor patients with suspected adrenal gland disorders, and guide appropriate treatment decisions by providing accurate biochemical evidence of abnormal hormone activity.

Additional Information

Also known as/ Other names: 24 Hour Urine Metanephrines, Urinary Metanephrines, 24 Hours, 24 Hr Metanephrine Test, Fractionated Metanephrines Urine Test
Parameters: 1
Recommended for: M/F/Others
Sample Type: 24 Hrs. Urine
Patient Preparation: Patient should strictly avoid Alpha- Methyldopa, Buspirone, Codeine, Isoproterenol metabolite, Mandelamine, L-dopa, Paracetamol, Metoclopramide, pepper, alcoholic beverages, tea/coffee, tobacco and strenuous exercise at least 72 hours before and during specimen collection.
Reports: 4 days

FAQs

Why is this test performed?

Doctors use it to diagnose pheochromocytoma or paraganglioma, rare tumors producing excess catecholamines, and to evaluate unexplained high blood pressure.

What does a high result mean?

Elevated metanephrines suggest excess catecholamine production, often linked to adrenal or extra‑adrenal tumors.

What does a normal result mean?

It indicates no abnormal catecholamine breakdown, reducing the likelihood of pheochromocytoma or related conditions.

Who should undergo this test?

Patients with unexplained hypertension, palpitations, headaches, or suspected adrenal tumors benefit from this test.

Is the test safe during pregnancy?

Yes, it is safe, as it only involves urine collection.

Can this test differentiate tumor types?

It indicates catecholamine excess but does not specify tumor type; imaging is needed.

Is the test useful for children?

Yes, it can be performed in children with suspected adrenal disorders.

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