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What is a PROTEIN-S, (FREE) ANTIGEN (IMMUNO-TURBIDIMETRY)?

The Protein-S (Free) Antigen by Immuno-Turbidimetry test is a specialized blood test used to measure the level of free Protein S, a natural anticoagulant that helps regulate blood clotting. Low levels of Protein S can increase the risk of abnormal clot formation, leading to conditions such as deep vein thrombosis or pulmonary embolism. Doctors recommend this test to evaluate unexplained clotting disorders, assess inherited or acquired deficiencies, and guide treatment decisions for patients with suspected thrombophilia.

Additional Information

Also known as/ Other names: Free Protein S Antigen Test, Protein S Free Antigen Assay, Free Protein S Level, Protein S Antigen (Free)
Parameters: 1
Recommended for: M/F/Others
Sample Type: Blood
Patient Preparation: Overnight fasting is preferred. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician.
Reports: Next Day

FAQs

Why is this test important?

It helps diagnose Protein S deficiency, which increases the risk of abnormal blood clots such as deep vein thrombosis or pulmonary embolism.

What does immuno-turbidimetry mean?

It is a laboratory method that measures antigen levels by detecting changes in light scattering caused by antigen-antibody complexes.

Who should undergo this test?

Patients with unexplained blood clots, family history of thrombophilia, or recurrent pregnancy loss may be advised to take this test.

Does a low Protein S level confirm deficiency?

Yes, persistently low levels suggest Protein S deficiency, but results must be interpreted with clinical findings.

Can Protein S deficiency be inherited?

Yes, it can be genetic, but acquired deficiencies may occur due to liver disease, pregnancy, or certain medications.

Can medications affect the test results?

Yes, anticoagulants, oral contraceptives, and pregnancy can lower Protein S levels, influencing results.

Can children undergo this test?

Yes, it can be performed safely in children suspected of having clotting disorders.

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