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What is a TB GOLD PLUS, INTERFERON GAMMA RELEASE ASSAY (IGRA)?

The TB Gold Plus, Interferon Gamma Release Assay (IGRA) is a modern blood test used to detect latent or active tuberculosis infection by measuring the immune system’s response to Mycobacterium tuberculosis. Unlike the traditional skin test, it provides higher accuracy and eliminates false positives caused by prior BCG vaccination. This test is performed to confirm TB exposure, guide treatment decisions, and support public health efforts in controlling tuberculosis, especially in high-risk or immunocompromised individuals.

Additional Information

Also known as/ Other names: M. tuberculosis IFN-γ Release Assay, TB Gold Plus IGRA, Interferon-Gamma Assay for TB, QuantiFERON-TB Gold Plus Assay, Tuberculosis IGRA (QFT-Plus)
Parameters: 1
Recommended for: M/F/Others
Sample Type: 6 mL Whole blood in 2 Green top (Sodium/Lithium heparin) tube
Patient Preparation: No prior preparation is needed
Reports: 3 Days

FAQs

Why is this test recommended?

Doctors recommend it to confirm TB exposure, especially in high-risk individuals, and to avoid false positives caused by prior BCG vaccination.

Who should undergo this test?

People with TB symptoms, close contacts of TB patients, immunocompromised individuals, or those requiring screening before immunosuppressive therapy should consider this test.

What conditions does the test detect?

It detects latent and active tuberculosis infection by identifying immune system response to TB antigens.

Can this test confirm a diagnosis?

It confirms TB infection but cannot distinguish between latent and active disease; further clinical evaluation is required.

Is the test affected by BCG vaccination?

No, unlike the skin test, IGRA is not influenced by prior BCG vaccination, making it more reliable.

Is genetic counseling necessary after testing?

No, this test does not involve genetic analysis; counseling is not required.

Can the test predict disease severity?

No, it only detects infection and does not predict severity or progression of tuberculosis.

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