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What is a VDRL, SERUM?

VDRL, Serum (Venereal Disease Research Laboratory) is a blood test used to screen for antibodies associated with syphilis, a sexually transmitted infection caused by Treponema pallidum. It is needed to help identify possible syphilis infection, assess individuals with symptoms or risk factors, and monitor response to treatment. Because VDRL is a non-treponemal test, reactive results are generally confirmed with a specific treponemal test.

Additional Information

Also known as/ Other names: Serum VDRL Test, Blood VDRL Test, Syphilis Screening Test (VDRL), Non-Treponemal Test (Serum)
Parameters: 1
Recommended for: M/F/Others
Sample Type: Blood
Patient Preparation: No prior preparation is needed
Reports: Same Day

FAQs

What is syphilis?

Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. Without appropriate treatment, it can progress through different stages and potentially affect multiple organs.

What does a reactive VDRL result mean?

A reactive result indicates that antibodies detected by the test are present. It does not by itself confirm syphilis because false-positive results can occur, so confirmatory testing is usually required.

What does a non-reactive VDRL result mean?

A non-reactive result means the test did not detect the antibodies measured by the assay. However, very early infection may sometimes produce a negative result.

Is VDRL a confirmatory test for syphilis?

No. VDRL is a non-treponemal test. A reactive result is generally evaluated with a treponemal-specific test to confirm whether syphilis infection is present.

What is the difference between VDRL and a treponemal test?

VDRL detects non-treponemal antibodies associated with cellular damage, while treponemal tests detect antibodies directed more specifically against Treponema pallidum.

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