Vitamin B1 (Thiamine) is a laboratory test that measures the level of thiamine, an essential water-soluble vitamin involved in energy production, carbohydrate metabolism, and normal nerve function. The test is needed to evaluate suspected thiamine deficiency, particularly in individuals with poor nutritional intake, malabsorption, chronic alcohol use, or certain medical conditions. Identifying deficiency can help guide appropriate supplementation and prevent neurological and metabolic complications.
A low result may indicate thiamine deficiency. The significance depends on symptoms, nutritional status, medical conditions, medications, and the laboratory's reference range.
Deficiency may cause fatigue, weakness, poor appetite, confusion, numbness or tingling, muscle weakness, and neurological problems. Severe deficiency can lead to serious complications.
Risk can be increased by inadequate nutrition, chronic alcohol use, malabsorption disorders, prolonged vomiting, certain gastrointestinal conditions, and some medical treatments.
Severe thiamine deficiency can affect cardiovascular function and may contribute to a condition known as wet beriberi, which can involve heart failure and fluid retention.
Beriberi is a disease caused by severe thiamine deficiency. It can primarily affect the nervous system or cardiovascular system, depending on the type and severity.